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Alessio Spinola

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Review Open access Sep 2026

Therapeutic potential of positive allosteric modulators of AMPA receptors in brain disorders.

α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPA receptors) are ionotropic glutamate receptors that mediate fast excitatory neurotransmission in the central nervous system. By translating chemical signals into rapid electrical depolarization, AMPA receptors, together with NMDA and kainate receptors,...

Alessio Spinola, Maria Italia, F. Gardoni · 0 citations

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