Alevtina A. Pinova

Senescence and SASP in the Stromal Microenvironment of Breast Cancer: Dual Role in Progression and Therapeutic Options.

Cellular senescence, a process characterized by the typically persistent cell-cycle arrest that occurs in response to DNA damage, plays a dual role in carcinogenesis. This complexity is predominantly influenced by the presence of senescent cancer-associated fibroblasts within the tumor microenvironment. While the induc...