Antitumor Effects of Melittin-Functionalized Fe3O4 Magnetic Nanoparticles in Collagen-I-Based Caco-2/BJ/HUVEC Spheroids Enhanced by Magnetic Hyperthermia
This study evaluated the integrated biochemical and ultrastructural response of three-dimensional colorectal cancer spheroids to magnetic hyperthermia (MH) mediated by melittin-functionalized Fe3O4 magnetic nanoparticles (MNPs-Mel). The spheroids comprised human Caco-2 colorectal adenocarcinoma cells, dermal fibroblast...