Alexa F. S. Gomberg

Positive control of the integrative and conjugative element Tn916 and its limited gene expression in transconjugants

Integrative and conjugative elements (ICEs) are widespread in bacteria and typically confer important phenotypes to their hosts. Following excision from the host chromosome, an ICE can transfer to a new cell through the element-encoded conjugation machinery (a type IV secretion system) to create a transconjugant. Tn916...