Pharmacogenomic variability represents an increasingly relevant determinant of therapeutic response, drug toxicity, and treatment failure in emergency and internal medicine. This study analyzed the clinical applicability of actionable gene–drug interactions associated with acute pharmacological decision-making, severe...
Dayanna Estefania Fernández Astudillo, Cristian David Castro Hernandez, María Alejandra Galindo Van Strahlen et al.· International science journa...· 0 citations
The reviewed evidence showed that systemic lupus erythematosus presented the broadest clinical heterogeneity, while neurological manifestations in Sjögren syndrome may precede classical glandular symptoms.
Jocelyne Keren Hinojosa Villanueva, Luis Felipe Espinal Pérez, Juan José Parra Serpa et al.· International science journa...· 0 citations
Retinal imaging may complement conventional vascular-risk assessment by identifying high-risk phenotypes and supporting targeted systemic evaluation, but it should not replace neuroimaging or specialized cardiovascular, neurological, or renal assessment.
Adrian Jhair Flores Equilea, Natalia Restrepo Hinestrosa, Juan José Parra Serpa et al.· IECCMEXICO· 0 citations
CRISPR has progressed from an experimental genome-engineering technology to a clinically relevant therapeutic platform, although its future impact will depend on the ability to combine molecular precision and durable therapeutic benefit with rigorous safety assessment, responsible governance, and equitable access acros...
Gabriel Alejandro Ortega Moreno, Gerardo Amaya Villagran, A. González et al.· International science journa...· 0 citations
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