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Author

Alexander Ciupa

2 papers indexed here

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Review Open access Aug 2026

Three privileged scaffolds, one pipeline: chalcones, pyrazolines and pyrazoles in drug discovery and fluorescent sensing

Chalcones, pyrazolines, and pyrazoles constitute a uniquely powerful discovery pipeline in which each is a privileged scaffold with distinct applications, while also serving as the synthetic precursor to the next. Despite a theoretical chalcone library exceeding 680 000 unique structures accessible from commercial star...

Alexander Ciupa · 0 citations
Open access Sep 2026

Electrospun poly(vinyl alcohol) nanofibers loaded with quaternary ammonium compounds for localized eradication of periodontal biofilms

Periodontitis is driven by polymicrobial biofilms and remains difficult to treat using systemic antibiotics, which fail to achieve therapeutic concentrations within periodontal pockets. In this study, we report on the fabrication of electrospun poly(vinyl alcohol) (PVA) nanofibers incorporating quaternary ammonium comp...

Ting Chen, Nicola Kelly, P. L. Oseliero et al. · 0 citations

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