Open access
Sep 2026
IGF2BP3 remodels RISC occupancy to control microRNA targeting in leukemia
Abstract IGF2BP3 is an oncofetal RNA-binding protein that promotes leukemogenesis, but the mechanisms by which it remodels post-transcriptional gene regulation remain incompletely understood. Because IGF2BP3 binds extensively within 3′ untranslated regions and has been implicated in microRNA (miRNA)-mediated regulation...
Lyna E. S. Kabbani, S. Kapoor, Gunjan Sharma et al.
· NAR Cancer · 0 citations