Author

Alexander Khoruts

2 papers indexed here

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Sep 2026

Hospitalisation in cirrhosis is linked to distinct gut microbiome structural and functional profiles: a multinational metagenomic study.

BACKGROUND Hospitalisations represent major clinical events in cirrhosis, yet prediction based on clinical variables alone remains limited. OBJECTIVE Given the role of the gut microbiome in disease progression, we evaluated whether gut metagenomic profiles are associated with 90-day hospitalisation and provide additi...

D. Nikitina, K. Suk, Aldo Torre et al. · Gut · 1 citation

Open access Aug 2026

Proximity-ligation metagenomics reveals differential plasmid and chromosomal antimicrobial resistance gene carriage in disrupted gut ecosystems

Summary Distinct ecological pressures shape accumulation of antimicrobial resistance genes (ARGs) and virulence genes in the gut microbiome. In this study, we used proximity ligation shotgun metagenomics to characterize bacterial host-mobilome relationships associated with antimicrobial resistance and virulence genes i...

Andrew J. Sommer, Benjamin Auch, Alexander Khoruts et al. · iScience · 0 citations