Autoimmune rheumatic diseases (ARDs) such as systemic lupus erythematosus and rheumatoid arthritis (RA) arise from aberrant immune responses that lead to chronic inflammation and tissue damage. Conventional treatments, including biological disease-modifying antirheumatic drugs (bDMARDs), often provide limited effective...
A. V. Poznyak, V. P. Karagodin, D. Borodko et al.· International Journal of Dru...· 0 citations
This paper advocates for a multi-target therapeutic approach in SS, aiming to mitigate the intricate cytokine network and restore glandular function, ultimately improving patient outcomes.
A. V. Poznyak, A. Vatlin, D. Borodko et al.· International Journal of Dru...· 0 citations
as it enhances brain energy metabolism and diminishes oxidative stress. Likewise, another investigation revealed that RV possesses anti-inflammatory and antioxidant characteristics. These properties can help suppress or prevent age-related cardiovascular diseases. Notably, RV has been shown to enhance cardiac contracti...
A. V. Poznyak, S.M. Kozlov, Gulalek A. Babayeva et al.· OnLine Journal of Biological...· 0 citations
Advances in understanding mitochondrial biology have enabled the development of novel therapeutic approaches, including activators of the PINK1/Parkin pathway, inhibitors of LRRK2 and α-synuclein aggregation, and strategies promoting mitochondrial biogenesis and intercellular transfer, offering potential for disease mo...
A. V. Poznyak, V. Pavshintsev, Aleksandra O. Utkina et al.· International journal of inn...· 0 citations
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