Open access
Aug 2026
Abatacept Reduces CD319+ (SLAMF7) Cytotoxic T Cells and Cytokine Production in Systemic Sclerosis.
Abatacept selectively modulates CD319/SLAMF7-expressing cytotoxic T cells and suppresses associated pro-fibrotic and pro-inflammatory cytokines, particularly in the fibroproliferative subtype, where CD319+ T cell reductions correlate with clinical improvement.
Mikel Gurrea-Rubio, Laura A. Cooney, Kohei Maeda et al.
· Arthritis & Rheumatology · 0 citations