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Author

Alexandra A. Dalina

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Open access Sep 2026

The p53-Associated Regulation of ATF4 mRNA Expression Involves p21 and p130 in a Stress-Dependent Manner

Highlights What are the main findings? Chemotherapeutic agents targeting p53 downregulate ATF4 mRNA in a stress-dependent manner. p21 and p130 contribute to the specific p53-dependent downregulation of ATF4 mRNA upon mitochondrial dysfunction. ATF4 mRNA levels are reduced under hypoxic conditions and partially restored...

Alexandra A. Dalina, Maria Shilyaeva, I. Kovaleva et al. · 0 citations

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