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Author

Alexandra Dananberg

1 paper indexed here

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Review Aug 2026

Advancing Human Artificial Chromosomes at the Dawn of Synthetic Genomics.

Human artificial chromosomes (HACs) are engineered, chromosome-scale DNA molecules that replicate and segregate autonomously in mammalian cells, offering a unique platform for large, stable, nonintegrating genetic delivery. The first generation of HACs emerged prior to synthetic genomics efforts, and their development...

Alexandra Dananberg, Gabriel J. Birchak, Ben E. Black · 0 citations

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