Genome-resolved metagenomics of traditional fermented beverages reveals biosynthetic diversity and informs the rational in silico design of probiotic synthetic communities
A bioprospecting pipeline applied to milk-based kefir, kombucha, pozol, and pulque is used, integrating targeted genomic mining of genes associated with the biosynthesis of B-group vitamins, short-chain fatty acids, natural products, and CAZymes with potential to enhance starch and dietary fiber utilization upon intest...