Author

Alexandros Makriyannis

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Open access Oct 2026

Efficacy profiling of structurally diverse cannabinoid receptor ligands across transducer-coupling assays

The full efficacy range of ligands at CB1 and CB2 (i.e., inverse agonists, neutral agonists, partial agonists, full agonists, and high-efficacy agonists) has been reported collectively across numerous laboratories and assay platforms. Canonical Gi/o and β-arrestin signaling have each been suggested to shape physiologic...

Soo Jung Oh, Christopher Lucaj, Kiera Truong et al. · bioRxiv · 0 citations

Open access Jul 2026

Targeted stool metabolomics suggests exploratory catecholamine- and tryptophan-linked metabolic features in autism spectrum disorder

Stool metabolite profiling revealed altered organization of tryptophan- and catecholamine-linked metabolic associations in ASD and identified a small metabolite panel with exploratory discriminative potential.

Kevin Liu, Huixi Li, Shaohan Zhang et al. · Frontiers in Neuroscience · 0 citations