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Author

Alexey Vatlin

2 papers indexed here

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Review Open access Sep 2026

CD80 as an Important Immune Mediator and Therapeutic Target in Atherosclerosis

Atherosclerosis is a chronic immune–inflammatory disease of the arterial wall in which antigen-presenting cells (dendritic cells, macrophages and B cells) present locally generated antigens, such as oxidized low-density lipoprotein, to plaque-infiltrating T cells. Full T-cell activation requires costimulation through t...

A. Blagov, Alexey Vatlin, D. Borodko et al. · 0 citations
Open access Sep 2026

Semaglutide Attenuates Inflammatory Macrophage Polarization and Promotes Changes Associated with Mitochondrial Biogenesis Through cAMP-Dependent Signaling

Background/Objectives: Chronic metabolic inflammation is associated with pro-inflammatory macrophage activation and mitochondrial dysfunction. Semaglutide, a widely used GLP-1 receptor agonist, has been reported to possess systemic anti-inflammatory properties, but its action on human macrophages, especially in the con...

V. Pavshintsev, Aleksandra Zh Erbaeva, Alexey Vatlin et al. · 0 citations

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