Sep 2026
Specific targeting of MR1-antigen complexes using nanobodies.
T cell receptor mimic (TCRm) antibodies that bind peptide-human leukocyte antigen complexes have great therapeutic potential. Major histocompatibility complex class I-related protein 1 (MR1) exhibits limited polymorphism and presents conserved metabolites, such as 5-OP-RU, derived from microbial riboflavin biosynthesis...
Hisham S. Hussain, S. Redmond, W. Awad et al.
· Science immunology · 0 citations