Review
Open access
Aug 2026
Decoding Treg diversity and dysfunction to advance Treg-based therapies in autoimmune and inflammatory diseases
Regulatory T cells (Tregs) orchestrate immune tolerance, tissue homeostasis, and tissue repair, and their dysfunction contributes to autoimmune and inflammatory diseases. Rather than representing a uniform lineage, Tregs comprise specialized cellular states shaped by developmental origin, antigen specificity, tissue lo...
Austin McKay, J. Cruz, Ian Taylor et al.
· Frontiers in Immunology · 0 citations