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Author

Ali Akbari

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Open access Jul 2026

TCR germline diversity reveals evidence of natural selection on variable and joining alpha chain genes 2250859

A near-complete map of human TCR germline diversity is generated, capturing over 94% of common alleles, and pervasive evidence of pathogen-driven natural selection on TCR genes is found, including diversifying selection across CDR and framework codons.

S. Mantena, Ali Akbari, S. Raychaudhuri · 0 citations

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