Ali M. Alhartomi

Integrating First-Principles Modeling with Explainable Machine Learning for Non-Isothermal Chromatography

Developing preparative chromatographic methods for multicomponent mixtures under nonisothermal conditions is difficult: mechanistic, physics-based models are accurate but computationally expensive, whereas data-driven surrogates are fast but often opaque and physically uninterpretable. We address this tension with an i...