Author

Alicia C. Lenzen

2 papers indexed here

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Oct 2026

Abstract B049: Landscape of genetic ancestry-associated active drugs unique to or shared by White and Hispanic children with group 3 medulloblastomas

This study uncovers reproducible genetic ancestry-based drug response profile between white and Hispanic G3 MBs, provides a biologic rational for mechanistic investigation of cancer disparities and supports the development of ancestry-informed precision therapeutic strategies for medulloblastoma.

Jin-Nan Chen, Yi-Ming Mei, Xin Zhai et al. · Cancer Epidemiology, Biomark... · 0 citations

Open access Aug 2026

A Phase I Trial of the ADAM-10 inhibitor, INCB007839, in Children with Recurrent/Progressive High-Grade Gliomas: A Report from the Pediatric Brain Tumor Consortium (PBTC-056)

Pediatric high-grade gliomas (pHGGs), including diffuse midline glioma (DMG) and diffuse intrinsic pontine glioma (DIPG), are the leading cause of central nervous system tumor-related morbidity and mortality in children. Neuronal activity promotes pHGG growth; one key mechanism is neuronal activity-regulated shed...

Alicia C. Lenzen, Sonia Partap, C. Billups et al. · Neuro-Oncology Pediatrics · 0 citations