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Alicia Goreth

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Open access Sep 2026

Spreading alpha-synuclein oligomers trigger astrocyte/microglial changes and astrocyte-glutamatergic neuron system dysfunction in an age-related manner

Parkinson’s disease (PD) is characterized by the progressive accumulation and spatio-temporal spread of α-synuclein (α-syn) oligomers and a progressive loss of dopaminergic neurons. Many studies showed a direct cytotoxic effect of α-syn oligomers on neurons. Other cell types including astrocytes or microglia were also...

Jaehyun LeeBae, Verena Bopp, Alicia Goreth et al. · 0 citations

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