Author

Alifujiang Hairulajiang

2 papers indexed here

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Review Open access Sep 2026

Immune-pressure redistribution in resistance to PD-1/PD-L1 blockade: mechanisms, biomarkers, and therapeutic design

A biomarker-guided strategy that combines tumor visibility, immune-cell state, spatial architecture, systemic inflammation, and early treatment dynamics to identify the dominant resistance topology is proposed to restore productive immune pressure while limiting compensatory escape and toxicity.

Xiao-Dong Wang, Jia-Yi Liu, Alifujiang Hairulajiang et al. · Molecular Cancer · 0 citations

Jul 2026

A carrier-within-a-carrier system with calcium nanoparticles encapsulated in β-cyclodextrin-polysaccharide hydrogel for verteporfin delivery and radiosensitization in orthotopic osteosarcoma.

A pH-responsive hydrogel reservoir is developed by integrating verteporfin (VP)-loaded CaCO3 nanoparticles (CaNPs) into a β-cyclodextrin-crosslinked polysaccharide hydrogel to achieve precise radiosensitization and immunomodulation, offering a promising approach to overcoming radioresistance and improving therapeutic o...

Jia-Yi Liu, Xue Tian, Alifujiang Hairulajiang et al. · Biomaterials · 0 citations