Alison L. Allan

Exploratory Transcriptomic Profiling of Triple-Negative Breast Cancer Patient-Derived Organoids Following Treatment with Radiation Alone and in Combination with Polo-like Kinase 4 Inhibition

Identification of novel biomarkers in triple-negative breast cancer (TNBC), one of the most aggressive breast cancer subtypes, is of critical clinical importance. Although radiation treatment (RT) is a cornerstone of TNBC treatment, resistance to RT compromises its therapeutic efficacy. Combining RT with radiosensitizi...