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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Alison W. Ashbrook

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Open access Oct 2026

A Novel Chemotype of Orally Active SARS-CoV-2 NSP14 Methyltransferase Inhibitors

The periodic emergence of human coronaviruses (hCoVs) necessitates direct-acting antivirals targeting underexploited viral proteins with broad-spectrum potential. Building on our discovery of TDI-015051, a first-in-class SARS-CoV-2 mRNA cap guanine-N7 methyltransferase (MTase) NSP14 inhibitor whose translational deve...

Cindy Meyer, Aitor Garzia, J. R. Merritt et al. · 0 citations
Open access Sep 2026

The Hao-Fountain syndrome gene USP7 restricts neurotropic orthoflavivirus entry through cell-intrinsic control of endosomal dynamics

Neurodevelopmental disorders are increasingly associated with immune phenotypes, including autoinflammation, immunodeficiency, and increased susceptibility to severe infection. To determine whether neurodevelopmental disorders-associated genes exert immune functions, we performed an arrayed siRNA screen targeting 28 ge...

Boris Bonaventure, Kyna Reyes, M. Martin et al. · 0 citations

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