Review
Open access
Aug 2026
Pan-tumor spatial transcriptomics reveals conserved properties of tumor organization
Summary Tumor microenvironments (TMEs) are compositionally and functionally heterogeneous, making it challenging to discover organizing structural principles. Through a study of 262 solid tumors profiled by spatial transcriptomics, we identify a conserved architecture where TMEs are partitioned into discrete, hierarchi...
Vivek Behera, Alexander Guzzetta, Hannah Giba et al.
· Cell Reports Medicine · 0 citations