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Author

Aloysius Wei-Yan Chia

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Open access Aug 2026

Cost-Effectiveness of Polygenic Risk Score-Guided Statin Therapy for Cardiovascular Disease Prevention in Singapore.

BACKGROUND Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of morbidity and mortality in Singapore. Under current guidelines, individuals at intermediate risk often do not receive preventive statin therapy despite potentially elevated genetic risk. Polygenic risk scores (PRSs) offer an opportunity to...

Irene Li Peng Ooi, Aloysius Wei-Yan Chia, Ying-Jie Chee et al. · 1 citation

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