Skip to content

Author

Altynbek Zhubanchaliyev

2 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Clinical trial Open access Nov 2026

Neoadjuvant PD-L1/TGF-β blockade can rapidly disrupt the tumor stroma in head and neck cancer patients

BACKGROUND TGF-β drives fibroblast activation in cancer and is a resistance biomarker to PD-1/PD-L1 blockade. METHODS Focusing on the tumor stroma, we characterized the impact of neoadjuvant treatment with bintrafusp alfa (BA), a dual PD-L1 and TGF-β inhibitor, in a window-of-opportunity study with 6 patients with head...

Caroline Hoffmann, Jan-Timon Werle, P. Sirven et al. · 0 citations
Open access Aug 2026

scROMA: batch-aware pathway-activity inference and a ground-truth simulation framework for single-cell transcriptomics

Background Pathway-activity analysis summarizes gene-level single-cell measurements into interpretable functional modules, but widely used methods lack an integrated significance framework, do not account for the batch effects that pervade multi-sample studies, and are not natively interoperable with Python-based workf...

Altynbek Zhubanchaliyev, Matthieu Najm, V. Laigle et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.