Alvaro G. Estévez

Tyrosine nitration: An emerging mechanistic landscape in neurodegeneration and cardiopulmonary disease

Protein tyrosine nitration is a post-translational modification associated with conditions of oxidative and inflammatory stress, driven by the production of reactive oxygen and nitrogen species (ROS and RNS). Once considered primarily a footprint of oxidative damage, tyrosine nitration is increasingly recognized as a s...