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Alvaro Luiz Helena

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Review Open access Aug 2026

Bioactive Natural and Synthetic Chalcones: Brazil as a Research Powerhouse in Discovery and Innovation

Chalcones (1,3‐diphenyl‐2‐propen‐1‐one) are open‐chain flavonoids recognized for their structural diversity and broad pharmacological activities. Electrophilic α,β‐unsaturated carbonyl systems and versatile substitution patterns on aromatic rings have positioned the chalcones as privileged structures in medicinal chemi...

P. R. Ozanique, Wellington Negri Tondato, Alvaro Luiz Helena et al. · 0 citations

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