The Cost of Safety: Balancing Biosafety and Histologic Integrity in Prion Research
Commentary Prion diseases, or transmissible spongiform encephalopathies (TSEs), represent a group of incurable and invariably fatal neurodegenerative disorders driven by the pathological misfolding of the prion protein (PrP) [1-6]. These diseases are characterized by a progressive clinical course and, despite their sig...