Author

Amanda Caruso

2 papers indexed here

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Review Open access Jul 2026

Patient-derived organoids in functional precision oncology: from experimental models to clinical decision-making

Despite major advances in high-throughput genomics, proteomics, and multimodal imaging, a substantial gap persists between molecular tumor characterization and clinically actionable therapeutic decision-making, partly due to the limitations of conventional preclinical models in capturing tumor heterogeneity and predict...

Amanda Caruso, A. Delvecchio, R. Memeo et al. · Frontiers in Endocrinology · 1 citation

Review Open access Aug 2026

Patient-Derived Organoids in Gastrointestinal Disease: Current Applications, Limitations, and Future Perspectives

The development of patient-derived organoids (PDOs) has substantially advanced the study of gastrointestinal diseases by providing three-dimensional human models that faithfully recapitulate the structural, molecular, and functional characteristics of native tissues. Unlike conventional two-dimensional cultures and ani...

Amanda Caruso, Yasmine Hamrouni, A. Delvecchio et al. · International Journal of Mol... · 0 citations