Open access
Nov 2026
The Molecular Interplay of Tau and Motor Proteins on Microtubules
Tau is a microtubule (MT)-associated protein essential for neuronal cytoskeletal organization and intracellular transport, yet how tau physically regulates motor proteins remains elusive. Here, we integrate single-molecule imaging, cryo-electron microscopy, and molecular dynamics (MD) simulations to investigate the mol...
Yi-Fei He, J. Peukes, Mert Golcuk et al.
· bioRxiv · 0 citations