CD55 promotes hematopoietic stem and progenitor cell survival in a mouse model of immune-mediated aplastic anaemia.
Idiopathic aplastic anaemia (AA) is a life-threatening autoimmune bone marrow (BM) failure syndrome characterized by a hypocellular BM and peripheral pancytopenia. While dysregulation of the complement system has been implicated in the pathogenesis of several autoimmune diseases, including rheumatoid arthritis and syst...