Ameeduzzafar Zafar

LC-MS/MS Method for Simultaneous Quantification of Zolpidem, Zopiclone, and Their Metabolites in Human Urine and Its Pharmacokinetic Application.

Zolpidem (Z1) and zopiclone (Z2) are widely prescribed for insomnia; but their misuse in drug-facilitated crimes presents significant forensic and clinical challenges. This study aimed to develop and validate a simple and sensitive LC-MS/MS method, coupled with dispersive liquid-liquid microextraction (DLLME), for the...

Nanofiber-Based Drug Delivery and Extracellular Matrix-Mimetic Platforms in Cancer Therapy: From Engineering Design to Clinical Translation.

The nanofiber-based drug delivery systems offer a high surface-area-to-volume ratio, tunable porosity, controllable degradation, and superior drug-loading capacity, making them promising platforms for precision cancer therapy. This review details the engineering design, fabrication methods and biomedical uses of nanofi...

Ameliorative effect of rufigallol on cisplatin-induced nephrotoxicity in rats: biochemical and histopathological evaluation.