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Author

Amir Zarrinpar

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Open access Sep 2026

Gut microbiome and metabolite profiles are associated with subsequent histologic MASH in a longitudinal mouse model

ABSTRACT Detecting metabolic dysfunction-associated steatohepatitis (MASH) before fibrosis develops remains a major challenge. We used a longitudinal streptozotocin/high-fat diet (STAM/HFD) mouse model to identify microbial and metabolic features that emerge before histological MASH onset. Integrative 16S rRNA and unta...

Stephany Flores Ramos, Kelly A. Fogelson, V. Muti et al. · 0 citations
Review Jul 2026

Engineering commensal microbes for host health.

This review summarized recent progress in the development of eLBPs across diverse disease indications, including inflammatory diseases, metabolic disorders, cancer, and infectious diseases, and proposed framework for the rational design of next-generation eLBPs that can more reliably translate from experimental systems...

Elizabeth A. Brown, Arianna Brevi, David Zong et al. · 0 citations

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