Serum metabolomics identifies ganglioside dysregulation and pyruvate dehydrogenase complex–related metabolic disturbances in pediatric drug-resistant epilepsy
Despite advances in epilepsy management, the exact causes of epilepsy remain unclear, and diagnostic biomarkers are still lacking. Besides, about one-third of cases involve drug-resistant epilepsy (DRE). This study employed untargeted metabolomics to identify potential metabolic signatures in the sera of ped...