Ammal Abbasi

Biological aging and the hidden architecture of early-onset cancer risk.

In a Nature Medicine study, Tian et al. identify larger biological age gaps associated with early-onset lung, colorectal, and uterine cancers across birth cohorts. These findings position biological age as an integrative marker of physiological dysregulation. Future work combining aging clocks and mutational signatures...

Mutagenic bypass of uracil-derived abasic sites underlies the SBS17 mutational signature