Ammar Abdul Aziz Alibeg

Design, in silico study, synthesis and cytotoxic evaluation of new isatin-thiazole-sulfanilamide derivatives as potential carbonic anhydrase inhibitors

One of the promising strategies in treatment of cancer is inhibiting the overexpression of carbonic anhydrase enzyme. This target represents a viable target for cancer therapy. In order to do this, four new compounds containing sulfonamide were prepared and manufactured utilizing different isatin derivatives. To choose...