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Author

Amogh Reddy Badikol

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Review Jul 2026

CRISPR-Cas9-based therapies for Huntington’s disease and Friedreich’s ataxia: mechanisms, advances, and future perspectives

Current CRISPR therapeutic strategies for HD and FRDA are examined, including allele-specific editing, transcriptional suppression, repeat excision, epigenetic reactivation, and emerging precision editing approaches such as base editing and prime editing.

Abha Ravikumar Mundada, Amogh Reddy Badikol, Karthik Mangu · 0 citations

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