As a non-steroidal aromatase inhibitor, letrozole is primarily used for treating estrogen-dependent breast cancer (BC). However, the long-term use of letrozole is limited due to severe adverse effects, including increased risks of cardiovascular disease and osteoporosis. A new bis-triazole compound derived from letrozo...
Wael A. A. Fadaly, Seif E. Ahmed, Fahad H. Baali et al.· Journal of Pharmacy and Scie...· 0 citations
These findings establish the nasal NLU formulation as a promising therapeutic platform to mitigate doxorubicin-induced cardiotoxicity and exhibit superior cardioprotective and antioxidant performance over the oral NFP.
H. Farouk, F. A. Abo El-Ela, Fahad H. Baali et al.· Journal of drug targeting (P...· 0 citations
Findings underscore the clinical potential of the intratumoral IPANF hydrogel as a highly efficient, localized, and safe platform for advanced breast cancer treatment and validate the superior therapeutic efficacy of the hydrogel.
Maha M. Ghalwash, Randa Mohammed Zaki, Obaid Afzal et al.· Journal of drug targeting (P...· 0 citations
The nasal GLDL spray is anticipated to be a promising and effective treatment option for BC by developing a nasal spray containing GCN-loaded liposomes (GLDL), and exhibited antiproliferative properties, as demonstrated by histopathological analysis of the formulation.
A. Al-Shammari, A. Sisi, Amr Gamal Fouad et al.· Naunyn-Schmiedeberg's Archiv...· 0 citations
It is suggested that the intratumor SLT formulation provides an effective option for the management of skin carcinoma and has the potential to improve localized therapeutic efficacy and mitigate systemic toxicity.
Rowayda Mohamed Ahmed, Maha M Ghalwash, Amr Gamal Fouad et al.· Journal of drug targeting (P...· 0 citations
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