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Author

Amr Gamal Fouad

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Oct 2026

Invasomes nanocarriers for targeted delivery of letrozole derivative: A novel strategy to mitigate breast cancer.

As a non-steroidal aromatase inhibitor, letrozole is primarily used for treating estrogen-dependent breast cancer (BC). However, the long-term use of letrozole is limited due to severe adverse effects, including increased risks of cardiovascular disease and osteoporosis. A new bis-triazole compound derived from letrozo...

Wael A. A. Fadaly, Seif E. Ahmed, Fahad H. Baali et al. · 0 citations
Sep 2026

Ufasomal Nanocarriers for Enhanced Cardiac Delivery of Nifedipine: A Novel Strategy to Mitigate Doxorubicin-Induced Cardiotoxicity in Breast Cancer Therapy.

These findings establish the nasal NLU formulation as a promising therapeutic platform to mitigate doxorubicin-induced cardiotoxicity and exhibit superior cardioprotective and antioxidant performance over the oral NFP.

H. Farouk, F. A. Abo El-Ela, Fahad H. Baali et al. · 0 citations
Aug 2026

Mitigating Breast Cancer with Intratumoral In Situ pH-responsive Abemaciclib-loaded Novasome Hydrogel.

Findings underscore the clinical potential of the intratumoral IPANF hydrogel as a highly efficient, localized, and safe platform for advanced breast cancer treatment and validate the superior therapeutic efficacy of the hydrogel.

Maha M. Ghalwash, Randa Mohammed Zaki, Obaid Afzal et al. · 0 citations
Jul 2026

Liposomes-enabled gemcitabine therapy for breast cancer: in vitro and in vivo studies.

The nasal GLDL spray is anticipated to be a promising and effective treatment option for BC by developing a nasal spray containing GCN-loaded liposomes (GLDL), and exhibited antiproliferative properties, as demonstrated by histopathological analysis of the formulation.

A. Al-Shammari, A. Sisi, Amr Gamal Fouad et al. · 0 citations
Jul 2026

Control of Skin Carcinoma via Sonidegib-loaded Transbilosomes.

It is suggested that the intratumor SLT formulation provides an effective option for the management of skin carcinoma and has the potential to improve localized therapeutic efficacy and mitigate systemic toxicity.

Rowayda Mohamed Ahmed, Maha M Ghalwash, Amr Gamal Fouad et al. · 0 citations

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