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Amrita Rajesh

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Open access Oct 2026

Monocyte-derived pro-angiogenic ocular macrophages identified by spatial transcriptomics are essential for choroidal neovascularization.

It is shown that this Monocyte-derived Pro-angiogenic Ocular Macrophage (MoPOM) subtype is upregulated in multiple ocular neovascular diseases across species, necessary for choroidal neovascularization, and is a potential therapeutic target to reduce destructive angiogenesis in the eye.

Andrew P. Voigt, Joyce Gong, Steven Droho et al. · 0 citations

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