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Author

Amy J. Naylor

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Open access Sep 2026

CD248/Endosialin regulates synovial fibroblast state to control coupling of inflammation and bone damage in murine models of immune-mediated inflammatory arthritis and ageing.

The data suggests that the high levels of CD248 expression seen on synovial fibroblasts provides a protective brake that attenuates bone damage by preventing the polarisation of emergent fibroblasts towards a destructive phenotype.

Samuel Kemble, C. Wehmeyer, James M. Brown et al. · 0 citations

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