An-Nie Dang

Schizophrenia-associated polygenic liability and structural genomic risk demonstrate broadly distributed neuropsychiatric associations in the All of Us Research Program

Background: Schizophrenia liability reflects both the aggregate effects of many common genetic variants and rare structural variation at recurrent neurodevelopmental copy-number variant (ND-CNV) loci. Although both components of genetic liability have been associated with schizophrenia and related phenotypes, it remain...