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An-Nie L. Chen

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Review Open access Aug 2026

Roles of exosome-mediated macrophage polarization in the hepatocellular carcinoma progression

Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality worldwide. The tumor microenvironment (TME) is a highly immunosuppressive niche shaped by aberrant angiogenesis, chronic inflammation, and extracellular matrix remodeling, which facilitates immune evasion and promotes HCC proliferation,...

An-Nie L. Chen, Minmin Zhu · 0 citations

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