Targeting the immunity-cell death axis: a multi-parametric network approach of traditional Chinese medicine against ischemia-reperfusion acute kidney injury
Acute kidney injury (AKI) remains a major clinical challenge, with persistently high incidence and mortality. Ischemia/reperfusion induced AKI (I/R-AKI) is the most common type, and its core pathological event is injury to renal tubular epithelial cells (RTECs). Energy depletion during ischemia and the burst of reactiv...