Lipid metabolism-immune crosstalk in glioblastoma: transcriptomic associations between PLIN2, PD-L1, and CSF1
Background: Glioblastoma is the most aggressive primary tumor of the adult central nervous system and is characterized by metabolic reprogramming and an immunosuppressive tumor microenvironment (TME) that contributes to therapeutic resistance, including limited response to immunotherapy. Evidence suggests that lipid st...