Open access
Oct 2026
H2A.J is an epigenetic driver of IL-17-associated inflammation in TH17 cells and keratinocytes
Psoriasis is a common autoinflammatory disease driven by excessive IL-17 expression. While the pathomechanism of the disease has been revealed, epigenetic factors contributing to psoriasis are less well understood. Here, we investigated the role of the poorly studied histone variant H2A.J in psoriasis. We found that H2...
T. Kübelbeck, Anna Stastny, N. Beumer et al.
· Molecular Biomedicine · 0 citations