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Ana Paula dos Anjos Lança

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Oct 2026

Functional assessment of patients with mitochondrial myopathy caused by POLG and mtDNA deletions

Background: Chronic Progressive External Ophthalmoplegia (CPEO) is a hallmark clinical manifestation of mitochondrial diseases, characterized by progressive weakness of the extraocular muscles and ptosis. Its genetic etiology is heterogeneous, commonly arising from either primary large-scale single mitochondrial DNA (m...

Tatiana Ribeiro Fernandes, Ana Paula dos Anjos Lança, André G. C. Martins et al. · 0 citations

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