Open access
Aug 2026
RGC-specific reversal of lipid peroxidation drives neuroprotection and vision restoration in optic nerve ischemia by targeting GPX4
Lipid peroxidation is established as mechanism of vision loss in NAION, and targeting GPX4 leads to neuroprotection and visual restoration and identifies GPX4 as a key molecular determinant of retinal ganglion cell resilience.
Ming Yang, Jie Pan, Shweta Modgil et al.
· bioRxiv · 0 citations