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Author

Anastasia M. Yakovleva

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Oct 2026

Substrate specificity and activity of extremotolerant tardigrade AP-endonuclease 1.

Tardigrades are microinvertebrates known for their extreme resilience to ionizing radiation, desiccation, and other environmental stresses. This tolerance is partly attributed to efficient DNA repair mechanisms. Here, we biochemically characterized the apurinic/apyrimidinic endonuclease 1 from Hypsibius exemplaris (hex...

Anastasia M. Yakovleva, Elena S. Mikushina, M. Meschaninova et al. · 0 citations

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